Dr. Ross A. Reynolds
- Ph.D. in Physics, 1983, University of Oregon.
- MS in Physics, 1978, University of Oregon.
- BS in Physics with Astronomy Concentration, 1973, Michigan State University.
- Professor of Physics, Grand Valley State University, 1990 - 2021 (Retired in 2021).
- Visiting Scientist, Van Andel Research Institute, 2003 to Present.
- Visiting Scientist Pharmacia and Upjohn, Kalamazoo, 1990 to 2003.
- NASA JOVE Fellow, Marshall Space Flight Center, 1990 to 1993.
- Assistant Professor of Physics, Colby College, 1983 to 1990.
- Post-Doctoral Teaching / Research Assistant, University of Oregon, 1975 to 1983.
- Associate Physicist, Johns Hopkins University's Applied Physics Lab, 1973 to 1975.
My teaching specialties include Introductory Calculus-based Physics, Solid State Physics, Astronomy, and Experimental Methods courses.
My professional field of expertise is Protein Crystallography, which draws techniques from Physics, Molecular Biology, Biochemistry, Chemistry, Mathematics and Engineering. I have worked with a group at NASA preparing crystallization experiments for the Shuttle. I've collaborated with researchers at Upjohn, which became Pharmacia, and more recently Pfizer on structure-based drug design. I'm currently work with the Structural Sciences group at Van Andel Institute, with a focus on cancer research. Over the years I've worked on structures of enzymes, electron transfer proteins, cell growth regulatory proteins and nuclear hormone receptor complexes. Ive also worked on a variety of instruments from fairly simple cameras using film to the latest CCD cameras using a a positron storage ring for an x-ray source. Research with Undergraduates
- Zhou, X.E., K.M. Suino-Powell, Y. Xu, C.W. Chan, O. Tanabe, S.W. Kruse, R. Reynolds, J.D. Engel, and H.E. Xu. "The orphan nuclear receptor TR4 is a vitamin A-activated nuclear receptor," J Biol Chem 286(4): 2877-2885 (2011).
- Suino, K, Peng, L, Reynolds, R., Yong, L., Cha, J., Repa, J, Kliewer, S., Xu, E., The Nuclear Xenobiotic Receptor CAR: Structural Determinants of Constitutive Activation and Heterodimerization. Molecular Cell, 2004, Volume 16, Number 6. 893 - 905.
- Reynolds, R.A., Watt, W., Watenpaugh, K.D. The Structures and Comparison of the Y98H (2.0) and Y98W (1.5) Mutants of Flavodoxin (Desulfovibrio vulgaris). Acta Cryst.,2001, D57, 527-535.
- Reynolds, R.A, Yem A.W., Wolfe, C.L., Diebel, M.R. Chidester, C.G., and Watenpaugh, K.D. Crystal Structure of the Catalytic Subunit of Cdc25B Required for G2/M Phase Transition of the Cell Cycle. Journal of Molecular Biology,1999, 293, 559-568.
- Structural determinants that mediate CAR/RXR heterodimerization and ligand dependent/independent activation Presented at 12th International Conference on Biological Inorganic Chemistry Satellite Meeting on Metallo-Membrane Proteins. Michigan State Univ. July, 2005.
- Initial Structural Results on Complex or CAR/RXR/TIF-2/TCPOBOP. Presented at the Symposium on the Evolution of Biomolecular Structure, Michigan State University, June 4th, 2004.
- The Anisotropic Refinement of the Y98W Mutant of Flavodoxin (Desulfovibrio vulgaris) Proceedings of the American Crystallographic Association . 2001.
- The Structure of the Catalytic Subunit of Cdc25B at 1.9 Resolution. International Crystallographic Union, Glasgow Scotland. August 1999.
- American Physical Society (APS)