ITRC PFAS Factsheets: Technical and Regulatory Guidance Document Interstate Technology & Regulatory Council, September 2023  

• Vapor-forming Per- and Polyfluoroalkyl Substances and the Vapor Intrusion Pathway (Updated December 2025)
• Regulations (Updated September 2023)
  • PFAS Environmental Media Values Table Excel file (Updated December 2025)
    • As of the September/October 2024 update, the PFAS Water and Soil Values tables includes the PFAS Air Criteria and has undergone cosmetic updates intended to make the table more user-friendly. The table is now titled the “PFAS Environmental Media Values tables” and the cosmetic updates include re-ordering individual PFAS by group (PFCAs, PFSAs and Other), as well as color-coding of groups of columns by topic, (e.g., location, criteria description, PFAS group, etc).
• Naming Conventions (Updated September 2023)
• History and Use (Updated September 2023)
• Fate and Transport and Physical and Chemical Properties (Updated September 2023)
  • Physical and Chemical Properties Table 4-1 for select PFAS Excel file (Updated July 2023)
• Sampling Precautions and Laboratory Analytical Methods (Updated September 2023)
• Site Characterization and Media-Specific Occurrence (Updated September 2023)
• Treatment Technologies and Methods (Updated September 2023)
• Aqueous Film-Forming Foam (Updated September 2023)
• Human and Ecological Health Effects and Risk Assessment (Updated September 2023)
• Risk Communication (Updated September 2023)
• Stakeholder Perspectives (Updated September 2023)
• Surface Water Quality (Updated September 2023)
• Biosolids and Per- and Polyfluoroalkyl Substances (Updated September 2023)

Green Science Policy Institute: Six Classes

• Detection of poly-and perfluooralkyl substances (PFASs) in US drinking water linked to industrial sites, military fire training areas, and wastewater treatment plants – 2016 – The drinking water of an estimated 6 million Americans contains PFAS at levels higher than the EPA says is safe. Scientists identify military bases, airports, and wastewater treatment plants as the major sources of contamination.
• Fluorinated Compounds in U.S. Fast Food Packaging – 2017 – Fluorinated chemicals found in about a third of take-out food packaging samples tested. Previous research has shown these chemicals can migrate from packaging into the food that people eat. (Press Release)
• Fluorinated Compounds in North American Cosmetics – 2021 – This widely read peer-reviewed study found that most waterproof mascara, liquid lipsticks, and foundations tested contained PFAS. (Press Release)
• An Overview of the Uses of Per- and Polyfluoroalkyl Substances (PFAS) – 2020 – This paper identifies more than 200 use categories and sub-categories for 1,400 different PFAS, demonstrating that these chemicals are used in nearly every industry branch and in more consumer products than previously known.

Global fluorinated alternatives - Insight

Although no single replacement can replicate all PFAS properties across all sectors, a diverse range of alternatives is emerging. Materials like acrylic or dendrimer-based repellents in textiles, sulfopolyester resins in coatings, and high-performance thermoplastics like PEEK offer viable, safer performance for a wide range of use cases. Adoption may require redesign and formulation adjustments.