Bioinformatics & HPC
The GVSU Applied Computing Institute's Bioinformatics and High-Performance Computing team is dedicated to advancing the field of computational biology through cutting-edge research and innovation. Our mission is to develop novel computational tools and techniques to analyze large-scale biological data sets and solve critical challenges in healthcare, agriculture, and environmental sciences.
Currently, Dr. DeBruine's lab is developing fast Non-negative Matrix Factorization algorithms for applications in bioinformatics and beyond. Special interests include single-cell experiment dimensional reduction and integration, hybrid NNLS/graph-based learning, genome/phenome meta-association, and novel approaches to model regularization.