Skip to main content
GVSU Blue Letters on campus

What are Opioids?

Opioids are a class of drugs derived from the opium poppy plant that are used for pain relief and non-prescription use. Opioids include synthetic opioids like heroin and “painkillers” including oxycodone, codeine, morphine, and many others. Addiction risk is high with opioids including prescription use.

Prevalence

  • More than 131 million opioid prescriptions were dispensed to American patients in 2022—with wide variation across states. Anyone who takes prescription opioids can become addicted to them. In fact, as many as one in four patients receiving long-term opioid therapy in a primary care setting struggles with opioid addiction.

  • According to the National Institute on Drug Abuse, opioid-involved overdose deaths rose from 21,089 in 2010 to 47,600 in 2017 and remained steady through 2019. There was a significant increase in 2020 with 68,630 reported deaths and again in 2021 with 80,411 reported overdose deaths.

  • Over 75% of the nearly 107,000 drug overdose deaths in 2021 involved an opioid.

Myths and Opioids

Are you worried about yourself or a friend?

If you are concerned about your own use of opioids, don't wait! Talk with the health care professionals who prescribed the medications for you. If you are concerned about family members or friends, urge them to talk to whoever prescribed their medications. Effective treatment of an opioid use disorder can reduce the risk of overdose and help a person who is misusing or addicted to opioid medications attain a healthier life.

Once addicted, it can be hard to stop. In 2016, more than 11.5 million Americans reported misusing prescription opioids in the past year

Opioid tolerance occurs when a person using opioids begins to experience a reduced response to medication, requiring more opioids to experience the same effect.

Opioid dependence occurs when the body adjusts its normal functioning around regular opioid use. Unpleasant physical symptoms occur when medication is stopped.

Opioid addiction (Opioid use disorder (OUD)) occurs when attempts to cut down or control use are unsuccessful or when use results in social problems and a failure to fulfill obligations at work, school, and home. Opioid addiction often comes after the person has developed opioid tolerance and dependence, making it physically challenging to stop using opioids and increasing the risk of withdrawal.

What are opioids?

What are opioids?

Opioid Overdose and Recovery

Opioid Overdose and Recovery

Page last modified July 27, 2026