The Lakers finished with 69 points, 15 points behind first-place Adams State. Sophomore Karlie Singleton placed eighth overall, running a time of 21:34.1, and junior Stacey Kandas ran a 22:10.9 for 19th place.
"I am extremely proud of the way the women ran," said head coach Jerry Baltes. "Mandi finished an amazing season with an outstanding performance today and led us to our best finish in school history.
"We had to overcome some obstacles in getting here and the California heat, but the women still managed to have a strong performance."
Sophomore Nate Peck led Grand Valley's men's team to a fourth-place finish. Peck finished 16th in a time of 32:10.9, and was closely followed by teammate Chris Pabst's 18th place finish in 32:23.7.