Recent publications (my undergraduate students are underlined and contain an “*”):

• Hujer, A. M., Hujer, K. M., Leonard, D. A., Powers, R. A., Wallar, B. J., Mack, A. R., Taracila, M. A., Rather, P. N., Higgins, P. G., Prati, F., Caselli, E., Kreiswirth, B. N., Fouts, D. E., & Bonomo, R. A. (2021) A comprehensive and contemporary “snapshot” of β-lactamases in carbapenem resistant Acinetobacter baumannii. Diagnostic Microbiology & Infectious Disease, Feb;99(2):115242. doi: 10.1016/j.diagmicrobio.2020.115242
• Curtis*, B. N., Smolen*, K. A., Barlow*, S. J., Caselli, E., Prati, F., Taracila, M. A., Bonomo, R. A., Wallar, B. J., & Powers, R. A. (2020). Structural insights into inhibition of the Acinetobacter derived cephalosporinase ADC-7 by ceftazidime and its boronic acid transition state analog. Antimicrobial Agents and Chemotherapy 64(12):1-13, doi: 10.1128/AAC.01183-20
• Caselli, E., Fini, F., Introvigne, M. L., Stucchi, M., Taracila, M. A., Fish*, E. R., Smolen*, K. A., Rather, P. N., Powers, R. A., Wallar, B. J., Bonomo, R. A., Prati, F. (2020) 1,2,3-Triazolylmethaneboronate: a Structure Activity Relationship Study of a New Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase (ADC-7).  ACS-Infect Dis. 6(7):1965-1975.
• Bouza*, A. A.; Swanson*, H. C.; Smolen*, K. A.; VanDine*, A. L.; Taracila, M. A.; Romagnoli, C.; Caselli, E.; Prati, F.; Bonomo, R. A.; Powers, R. A.; Wallar, B. J., (2018) Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase. ACS Infect Dis 4 (3), 325-336. DOI: 10.1021/acsinfecdis.7b00152.
• Caselli, E.; Romagnoli, C.; Powers, R. A.; Taracila, M. A.; Bouza*, A. A.; Swanson*, H. C.; Smolen*, K. A.; Fini, F.; Wallar, B. J.; Bonomo, R. A.; Prati, F., (2018) Inhibition of Acinetobacter-Derived Cephalosporinase: Exploring the Carboxylate Recognition Site Using Novel beta-Lactamase Inhibitors. ACS Infect Dis 4 (3), 337-348. DOI: 10.1021/acsinfecdis.7b00153.
• Powers, R. A.; Swanson*, H. C.; Taracila, M. A.; Florek*, N. W.; Romagnoli, C.; Caselli, E.; Prati, F.; Bonomo, R. A.; Wallar, B. J., (2014) Biochemical and structural analysis of inhibitors targeting the ADC-7 cephalosporinase of Acinetobacter baumannii. Biochemistry 53 (48), 7670-9. DOI: 10.1021/bi500887n.

Recent presentations (my undergraduate students are underlined and contain an “*”):

• Beardsley*, T. J., Fernando, M.C., Fish*, E. R., June, C.M., Rather, P.N., Caselli, E., Prati, F., Hujer, A. M., Bonomo, R. A., Powers, R., Wallar, B.J. (2021) Kinetic and structural characterization of ADC variants from carbapenem-resistant Acinetobacter baumannii World Microbe Forum, June 20-24, iPoster WMF21-3101.
• Fernando*, M. C., Beardsley*, T. J., Fish*, E. R., Hujer, A. M., Bonomo, R. A., Powers, R., Wallar, B.J.. (2020) Kinetic and structural characterization of novel ADC variants from carbapenem-resistant Acinetobacter baumannii 40^th Midwest Enzyme Chemistry Conference, Virtual.
• Ruiz*, V.J., Fernando*, M.C., Fish*, E.R., Caselli, E., Prati, F., Hujer, A.M., Bonomo, R.A., Powers, R.A., Wallar, B.J. (2020) Kinetic and structural characterization of ADC variants from carbapenem resistant Acinetobacter baumannii. ASM Microbe, June 18-22, Chicago, IL (conference cancelled).
• June, C.M., Curtis*, B.N., Caselli, E., Prati, F., Bethel, C.R., Bonomo, R.A., Wallar, B.J., Leonard, D.A., Powers, R.A. (2020) X-ray crystal structure of the carbapenem-hydrolyzing class D b-lactamase OXA-24/40 in complex with a ceftazidime-like boronic acid inhibitor. ASM Microbe, June 18-22, Chicago, IL (conference cancelled).
• Caselli, E., Introvigne, M.L., Fini, F., Taracila, M.A., Fish*, E.R., Smolen*, K.A., Rather, P., Powers, R.A., Wallar, B.J., Bonomo, R.A., Prati, F. (2020) 1,2,3-Triazolylmethaneboronate: a SAR study of a New Class of β-Lactamase Inhibitors in Acinetobacter baumannii. ASM Microbe, June 18-22, Chicago, IL (conference cancelled).
• Fish*, E. R., Caselli, E., Taracila, M.A., Bonomo, R. A., Prati, F., Powers, R., Wallar, B. J. (2019) Characterization of Novel Triazole-Containing Boronic Acid Transition State Inhibitors (BATSIs) of Acinetobacter-derived Cephalosporinase (ADC-7). Protein Society Annual Meeting, Seattle, WA.
• Curtis*, B. N., Caselli, E., Taracila, M.A., Bonomo, R. A., Prati, F., Powers, R., Wallar, B. J. (2019) Structural Characterization of Acinetobacter-Derived Cephalosporinase-7 in Complex With Ceftazidime and its Transition State Analog. Protein Society Annual Meeting, Seattle, WA.
• Fish*, E. R., Curtis*, B. N., Smolen*, K. A., Caselli, E., Prati, F., Powers, R., Wallar, B. J. (2018) Structure-based analysis of inhibitors of Acinetobacter-derived cephalsporinase-7 (ADC-7), a unique class C β-lactamase. 38^th Midwest Enzyme Chemistry Conference, Northwestern University, Evanston, IL.
• Taracila, M.A., Caselli, E., Prati, F., Powers, R.A., Wallar, B.J., Bonomo, R.A. (2017) Active Site Interactions of Boronic Acid Inhibitors of Acinetobacter-Derived Cephalosporinase (ADC-7) Class C β-lactamases-Lessons for New Drug Design.  American Society for Microbiology – Annual “Microbe” Conference, New Orleans, LA.
• Wallar, B.J., Prati, F., Caselli, E., Romagnoli, C., Swanson*, H.C., Bouza*, A., VanDine*, A., Bonomo, R.A., Powers, R.A. (2015) Exploring the structure-activity relationship of a series of boronic acid inhibitors of Acinetobacter-derived cephalosporinase ADC-7.  55^th  Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, CA.
• Powers, R.A., Prati, F., Caselli, E., Romagnoli, C., Swanson*, H.C., Bouza*, A., Smolen*, K., Bonomo, R.A., Wallar, B.J. (2015) Structure-function analysis of R2 substituents in boronic acid inhibitors of Acinetobacter-derived cephalosporinase (ADC-7). 55^th  Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, CA.
• Swanson*, H. C., Prati, F., Caselli, E., Romangoli, C., Taracila, M. A., Bonomo, R. A., Powers, R., Wallar, B.J. (2014) X-ray crystal structure of the extended-spectrum class C β-lactamase, ADC-7, in apo form and in complex with a boronic acid transition state analog. American Chemical Society Annual Meeting, Dallas, TX.
• Wallar, B.J., Prati, F., Caselli, E., Romangoli, C., Swanson*, H. C., Taracila, M. A., Bonomo, R. A., Powers, R. (2013) Acinetobacter spp. class C cephalosporinase (ADC-7) is inhibited by boronic acid transition state analogs. 53^rd Interscience Conference on Antimicrobial Agents and Chemotherapy, Denver, CO.
• Baggett*, V.L., Docter*, B.E., Leonard, D., Powers, R., Wallar, B.J. (2013) The N152T mutation in the class C β-lactamase, AmpC, can serve as a substrate selectivity switch. American Society for Biochemistry and Molecular Biology Annual Meeting, Boston, MA.
• Porambo*, A. R., Florek*, N., Powers, R., Wallar, B.J. (2013) The X-ray crystal structure of the Acinetobacter-Derived Cephalosporinase, ADC-7. American Society for Biochemistry and Molecular Biology Annual Meeting, Boston, MA.
• Docter*, B.E., Anwar, M., Leonard, D., Powers, R., Wallar, B.J.  (2013) Probing the binding site in the antibiotic resistance enzyme, AmpC, β-lactamase.  Enzyme Mechanisms Conference, Coronado, CA.